Ultra-processed
 foods are not known for their health qualities. We know this, yet it's 
hard to resist the doughnuts your kind colleague brought into the 
office. Now, research published Wednesday in the BMJ may give you at least a longer pause before you pick the pink one with sprinkles.
Researchers discovered that people who eat more ultra-processed foods
 have a higher risk of cancer. Such foods are the ones with 
unrecognizable and unpronounceable words on the list of ingredients -- 
anything from the candy that turns your tongue blue to 
healthier-sounding canned soups packed with artificial flavors, 
additives or emulsifiers. Most food is processed to some degree, but 
ultra-processed foods are typically much more calorie-, sodium- and sugar-packed.
What
 the scientists found was that a 10% increase in the proportion of 
ultra-processed foods in the diet was associated with a significant 
increase of greater than 10% in risks for overall cancer and breast 
cancer. 
Sanders,
 who was not involved in the study, said the authors made statistical 
adjustments to accommodate for some of that, but he cautions that "the 
approach of categorizing dietary patterns that depend on industrially 
processed food in relation to disease risk is novel but probably needs 
refining before it can be translated into practical dietary advice."
Researchers discovered that people who eat more ultra-processed foods
 have a higher risk of cancer. Such foods are the ones with 
unrecognizable and unpronounceable words on the list of ingredients -- 
anything from the candy that turns your tongue blue to 
healthier-sounding canned soups packed with artificial flavors, 
additives or emulsifiers. Most food is processed to some degree, but 
ultra-processed foods are typically much more calorie-, sodium- and sugar-packed.
Research has long showed that people who live on ultra-processed food tend to be more obese and overweight. They're also more likely to have heart and circulation problems or diabetes, studies have found. Eating a lot of processed meat like hot dogs has also been tied to an increased risk of colorectal cancer.
Researchers saw this new cancer link when they analyzed 24-hour dietary records of nearly 105,000 adults in the NutriNet-Sante cohort,
 a general population group in France. The individuals recorded what 
they ate from a list of 3,300 food items that were then categorized by 
how processed they were, using a system called NOVA. 
What
 the scientists found was that a 10% increase in the proportion of 
ultra-processed foods in the diet was associated with a significant 
increase of greater than 10% in risks for overall cancer and breast 
cancer. 
"Ultra-processed
 fats and sauces, sugary products and drinks were associated with an 
increased risk of overall cancer," the study says. "Ultra-processed 
sugary products were associated with an increased risk of breast 
cancer."
People who tended
 to eat more ultra-processed food also tended to smoke more and exercise
 less than the others, but the authors controlled for these issues and 
still found the elevated cancer risk. 
"It
 was quite surprising, the strength of the results. They were really 
strongly associated, and we did many sensitive analysis and adjusted the
 findings for many co-factors, and still, the results here were quite 
concerning," study co-author Mathilde Touvier said. 
"What
 people eat is an expression of their lifestyle in general and may not 
be causatively linked to the risk of cancer. So it is necessary to rule 
out what are called cofounding factors," said Tom Sanders, scientific 
governor of the British Nutrition Foundation and an emeritus professor 
at King's College London. 
Sanders,
 who was not involved in the study, said the authors made statistical 
adjustments to accommodate for some of that, but he cautions that "the 
approach of categorizing dietary patterns that depend on industrially 
processed food in relation to disease risk is novel but probably needs 
refining before it can be translated into practical dietary advice."
The nonprofit trade group Association of Food Industries did not respond to requests for comment.
Marji McCullough, strategic director of nutritional epidemiology at the American Cancer Society, suggests caution about interpreting what is responsible for the cancer risk associated with ultra-processed food. 
"This
 study doesn't mean that people should think 'if I eat this cracker, I'm
 going to get cancer,' " McCullough said. "The overriding message of 
this study was really to look at an overall diet pattern rather than a 
specific ingredient, and it supports a lot of what we already know." 
For
 example, she said, people eating more highly processed foods are 
probably eating fewer healthy foods, which may help prevent cancer. 
Nutritionists recommend a diet rich in whole grains, whole fruits and 
vegetables instead of foods that have little nutritional value. 
Touvier
 also noted that it's an observational study, meaning scientists don't 
know what exactly is causing the increased cancer risk, but her group at
 the Sorbonne Paris Cité Epidemiology and Statistics Research Center
 plans to look closer at what the connection may be. "The challenge now 
is to disentangle the different foods and understand this relationship 
to see what specifically is having this effect."
Animal
 studies have shown that some additives are "quite good candidates" for 
being carcinogenic, Touvier said, "but that would need to be seen if 
they are also carcinogenic in the human population." 

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